by AACR
Targeted radiation delivery is a viable option for cancer patients whose intolerance of high-dose chemotherapy is a barrier to potentially curative hematopoietic cell transplantation (HCT),...
by Blood Advances
Scientists have developed a syngeneic mouse model that accurately reflects antitumor activity and adverse effects detected following different types of antibody-based human immunotherapy.
by AACR
Collectively harnessing the different properties of interleukin 15 and 21 can boost the efficacy of engineered T cells against solid tumors, according to researchers. They employed mouse models of...
by AACR
Researchers say prolonged survival is possible in patients with high-risk leukemia or MDS who receive targeted radioimmunotherapy prior to haploidentical hematopoietic cell transplantation...
by Blood Advances
A promising chimeric antigen receptor (CAR) construct designed to combat CD30-positive lymphoma demonstrated low efficacy and significant toxicity in clinical study, limiting its value as a...
by ASTCT Science Highlights
Sun F, Cheng Y, Chen J-R, et al. BCMA- and CST6-Specific CAR T Cells Lyse Multiple Myeloma Cells and Suppress Murine Osteolytic Lesions. Journal of Clinical Investigation. 2023; (doi:...